Mariana Igoillo-Esteve Selected Research

tRNA Methyltransferases

11/2018	Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
10/2013	tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans.

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Mariana Igoillo-Esteve Research Topics

Disease

8	Type 2 Diabetes Mellitus (MODY) 01/2021 - 12/2009
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2015 - 01/2011
3	Friedreich Ataxia (Friedreich's Ataxia) 01/2020 - 12/2012
3	Inflammation (Inflammations) 12/2018 - 02/2011
3	Microcephaly 11/2018 - 10/2013
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 12/2012
2	Rare Diseases (Rare Disease) 01/2021 - 04/2015
2	Insulin Resistance 08/2013 - 10/2008
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2020
1	Glucose Intolerance 01/2017
1	Wolcott-Rallison syndrome 11/2015
1	Intellectual Disability (Idiocy) 11/2015
1	Autoimmune Diseases (Autoimmune Disease) 01/2012
1	B-Cell Lymphoma (Lymphoma, B Cell) 02/2011
1	African Trypanosomiasis (Nagana) 12/2010
1	Chagas Disease (American Trypanosomiasis) 12/2007

Drug/Important Bio-Agent (IBA)

5	CytokinesIBA 01/2021 - 01/2011
3	Transfer RNA (tRNA)IBA 01/2021 - 10/2013
3	Nonesterified Fatty Acids (NEFA)IBA 08/2020 - 12/2009
3	FrataxinIBA 01/2020 - 12/2012
2	Insulin (Novolin)FDA Link 01/2021 - 10/2008
2	Glucose (Dextrose)FDA LinkGeneric 12/2018 - 08/2013
2	tRNA MethyltransferasesIBA 11/2018 - 10/2013
1	Pharmaceutical PreparationsIBA 01/2021
1	PalmitatesIBA 08/2020
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020
1	Exenatide (Byetta)FDA Link 01/2020
1	IronIBA 01/2020
1	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2020
1	IncretinsIBA 01/2020
1	SulfurIBA 01/2020
1	Guanabenz (BR 750)FDA Link 01/2017
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2015
1	Phosphotransferases (Kinase)IBA 11/2015
1	InterferonsIBA 02/2011
1	Transcription Factors (Transcription Factor)IBA 02/2011
1	ProlactinIBA 02/2011
1	Glucagon-Like Peptides (Enteroglucagon)IBA 12/2009

Therapy/Procedure

2	Therapeutics 12/2018 - 04/2015
2	Drug Therapy (Chemotherapy) 12/2010 - 12/2007
1	Transplantation 02/2011